{"created":"2023-05-15T14:06:34.876437+00:00","id":1806,"links":{},"metadata":{"_buckets":{"deposit":"6a578574-9d13-4d29-ae96-e8dbdf17ff17"},"_deposit":{"created_by":19,"id":"1806","owners":[19],"pid":{"revision_id":0,"type":"depid","value":"1806"},"status":"published"},"_oai":{"id":"oai:dwcla.repo.nii.ac.jp:00001806","sets":["20:21","224:340"]},"author_link":["6154","6155","6152","6153"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-07-27","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"136","bibliographicPageStart":"128","bibliographicVolumeNumber":"35","bibliographic_titles":[{"bibliographic_title":"総合文化研究所紀要"},{"bibliographic_title":"Bulletin of Institute for Interdisciplinary Studies of Culture Doshisha Women’s College of Liberal Arts","bibliographic_titleLang":"en"}]}]},"item_10002_description_19":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10002_description_35":{"attribute_name":"ID","attribute_value_mlt":[{"subitem_description":"AN10052143-20200605-128","subitem_description_type":"Other"}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Dissolution test is mandatory to guarantee the quality of the generic pharmaceutical tablets, and generic pharmaceutical tablets must comply with this dissolution test to be approved. However, in this test, it is not clear what type of elution behavior to take, only by\nspecifying the dissolution rate at a fixed time. In this study, we aimed to clarify elution behavior of loxoprofen sodium 60 mg tablet (24 items) and nitrendipine 5 mg tablet (15 items) by measuring dissolution rate with time according to dissolution test of the Japanese\nPharmacopeia with some modification. Both drug showed good dissolution. The original brand loxoprofen tablets had comparatively small variation among tablets in elution behavior. For generic loxoprofen tablets, some of the dissolution rates were faster or slower. In some generic items, variations in elution behaviors were observed within the same item. In the original brand nitrendipine tablets, elution behavior showed slowly until 5 minutes, and then fast elution, and there was variation between the tablets by 15 minutes. Many of generic\nnitrendipine tablets showed variations in 5 to 15 minutes in elution behavior within the same item, but some showed little variations between tablets within the same item.","subitem_description_type":"Abstract"}]},"item_10002_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"論文","subitem_description_type":"Other"}]},"item_10002_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15020/00001760","subitem_identifier_reg_type":"JaLC"}]},"item_10002_link_30":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_link_text":"同志社女子大学研究者データベース - 成橋和正","subitem_link_url":"https://research-db.dwc.doshisha.ac.jp/rd/html/japanese/researchersHtml/2705/2705_Researcher.html"},{"subitem_link_text":"同志社女子大学研究者データベース - 芝田信人","subitem_link_url":"https://research-db.dwc.doshisha.ac.jp/rd/html/japanese/researchersHtml/2697/2697_Researcher.html"}]},"item_10002_publisher_32":{"attribute_name":"出版地","attribute_value_mlt":[{"subitem_publisher":"京都"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"同志社女子大学総合文化研究所 (学術研究支援課)"}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10052143","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09100105","subitem_source_identifier_type":"ISSN"}]},"item_10002_text_27":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"同志社女子大学・薬学部・医療薬学科"},{"subitem_text_value":"同志社女子大学・薬学部・医療薬学科"}]},"item_10002_text_28":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences,Doshisha Womenʼs College of Liberal Arts"},{"subitem_text_value":"Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences,Doshisha Womenʼs College of Liberal Arts"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"成橋, 和正"},{"creatorName":"ナルハシ, カズマサ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"6152","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"芝田, 信人"},{"creatorName":"シバタ, ノブヒト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"6153","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naruhashi, Kazumasa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6154","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shibata, Nobuhito","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6155","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-08"}],"displaytype":"detail","filename":"AN10052143-20200605-128.pdf","filesize":[{"value":"3.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"先発医薬品・後発医薬品（錠剤）の溶出挙動の比較と評価","url":"https://dwcla.repo.nii.ac.jp/record/1806/files/AN10052143-20200605-128.pdf"},"version_id":"9b91de99-2551-40a6-8836-c93c9ff697ef"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"先発医薬品・後発医薬品（錠剤）の溶出挙動の比較と評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"先発医薬品・後発医薬品（錠剤）の溶出挙動の比較と評価"},{"subitem_title":"Comparison and evaluation of elution behavior of","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"19","path":["21","340"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-06-05"},"publish_date":"2020-06-05","publish_status":"0","recid":"1806","relation_version_is_last":true,"title":["先発医薬品・後発医薬品（錠剤）の溶出挙動の比較と評価"],"weko_creator_id":"19","weko_shared_id":-1},"updated":"2023-05-15T14:39:35.244866+00:00"}