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oai:dwcla.repo.nii.ac.jp:00001962 2023-05-15T14:33:15Z 219:349 25:28

コレステロール添加食投与ラットの肝脂肪蓄積に及ぼす焙煎度の異なるコーヒー豆抽出物の影響 Effects of the extracts of coffee beans roasted at different degrees on liver fat accumulation in rats fed cholesterol-added diets 仲佐, 輝子 ナカサ, テルコ NAKASA, Teruko 泉谷, 祐希 イズタニ, ユウキ 坂野, 友香 サカノ, トモカ 塚本, 万智 ツカモト, マチ 川上, 小百合 カワカミ, サユリ 高田, 智美 タカタ, サトミ IZUTANI, Yuki SAKANO, Tomoka TSUKAMOTO, Machi KAWAKAMI, Sayuri TAKATA, Satomi コーヒー豆抽出物 非アルコール性脂肪肝 コレステロール添加食 脂質代謝 application/pdf AA11325308-20201130-36 We examined the effects of the extracts of coffee beans roasted at different degrees on the lipid metabolism of rats fed cholesterol（Cho）-added diets. Fatty livers along with a significant increase in triacylglycerol（TG）and Cho levels were observed in rats belonging to the C（Cho-added diet）group. Although the Cho level was slightly decreased in the S group, with the addition of shallow-roasted coffee bean extract to Cho-added diet, carnitine palmitoyltransferase activity showed a significantly high value, and the amount of TG was significantly reduced. In contrast, with the addition of deep-roasted coffee bean extract to Cho-added diet in the D group, fatty acid synthase activity showed a significantly lower value, TG and Cho levels were significantly reduced, and a reduction in fatty liver was observed. Moreover, since the levels of lipid peroxide in plasma and liver decreased in both S and D groups, compared to the C group, there is a possibility that roasted coffee bean extracts may suppress the progression to nonalcoholic steatohepatitis. 原著論文 京都 同志社女子大学生活科学会 2020-02-20 jpn departmental bulletin paper https://doi.org/10.15020/00001907 https://dwcla.repo.nii.ac.jp/records/1962 10.15020/00001907 AA11325308 13451391 同志社女子大学生活科学 DWCLA human life and science 53 36 44 https://dwcla.repo.nii.ac.jp/record/1962/files/AA11325308-20201130-36.pdf application/pdf 1.5 MB 2020-12-02